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Population genetics of immune-related multilocus copy number variation in Native Americans
(Royal Society Publishing, 2017)
While multiallelic copy number variation (mCNV) loci are a major component of genomic variation, quantifying the individual copy number of a locus and defining genotypes is challenging. Few methods exist to study how mCNV ...
Different Pollinators' Functional Traits Can Explain Pollen Load in Two Solitary Oil-Collecting Bees
(MDPI Multidisciplinary Digital Publishing Institute, 2020-10)
Pollinators' features, especially those with a functional role during the pollination process, have been shown to be a good predictor of pollen load for some bee species, but little is known about solitary bees. Here, I ...
Help or hindrance? The evolutionary impact of whole-genome duplication on immunogenetic diversity and parasite load
(2020-12-01)
Whole-genome duplication (WGD) events occur in all kingdoms and have been hypothesized to promote adaptability. WGDs identified in the early history of vertebrates, teleosts, and angiosperms have been linked to the large-scale ...
Development of a novel protocol based on blood clot to improve the sensitivity of qPCR detection of toxoplasma gondii in peripheral blood specimens
(American Society of Tropical Medicine and Hygiene, 2019)
Quantitative polymerase chain reaction (qPCR) for Toxoplasma gondii multicopy genes has emerged as a promising strategy for sensitive detection of parasite DNA. qPCR can be performed from blood samples, which are minimally ...
Oenococcus oeni in chilean red wines: technological and genomic characterization
(Frontiers media SA, 2018)
The presence and load of species of LAB at the end of the malolactic fermentation (MLF) were investigated in 16 wineries from the different Chilean valleys (Limari, Casablanca, Maipo, Rapel, and Maule Valleys) during 2012 ...
Non-Specific Antibodies Induce Lysosomal Activation in Atlantic Salmon Macrophages Infected by Piscirickettsia salmonis
(Frontiers Media S.A., 2020-11)
Piscirickettsia salmonis, an aggressive intracellular pathogen, is the etiological agent of salmonid rickettsial septicemia (SRS). This is a chronic multisystemic disease that generates high mortalities and large losses ...
Testosterone-loaded GM1 micelles targeted to the intracellular androgen receptor for the specific induction of genomic androgen signaling
(Elsevier Science, 2020-12)
Androgens play a central role in homeostatic and pathological processes of the prostate gland. At the cellular level, testosterone activates both the genomic signaling pathway, through the intracellular androgen receptor ...
Integração de dados para avaliação da qualidade da anotação dos genes codificadores de proteínas em eucariotos
(Universidade Federal de Minas GeraisBrasilICB - INSTITUTO DE CIÊNCIAS BIOLOGICASPrograma de Pós-Graduação em BioinformaticaUFMG, 2019-06-10)
Whole genome sequencing studies are becoming common in view of the low cost of the sequencing technologies currently available. In consequence, the volume of genome projects is rapidly increasing, and complete genomes are ...
Respiratory syncytial virus genotypes, host immune profiles, and disease severity in young children hospitalized with bronchiolitis
(Oxford University Press, 2018)
Background. Data on how respiratory syncytial virus (RSV) genotypes influence disease severity and host immune responses is limited. Here, we characterized the genetic variability of RSV during 5 seasons, and evaluated the ...
Genomic loads and genotypes of respiratory syncytial virus: Viral factors during lower respiratory tract infection in chilean hospitalized infants
(MDPI AG, 2017)
© 2017 by the authors. Licensee MDPI, Basel, Switzerland.The clinical impact of viral factors (types and viral loads) during respiratory syncytial virus (RSV) infection is still controversial, especially regarding newly ...